The STRIDER trial is a randomised control trial which aims to find a treatment for intrauterine growth restriction (IUGR).

What is STRIDER?

STRIDER stands for Sildenafil Therapy In Dismal Prognosis Early-Onset Intrauterine Growth Restriction. Researchers working on the STRIDER trial will determine if oral sildenafil citrate, the medicine commonly known as Viagra, can help mothers diagnosed with intrauterine growth restriction (IUGR).

Severe IUGR in pregnancy is caused by reduced blood flow to the placenta and usually results in preterm birth. An extremely early birth can cause infant mortality or long-term health problems for a child. 

A mother clasping her baby's hand
How does STRIDER work?

STRIDER is a randomised control trial. This means that mothers diagnosed with IUGR will take either oral sildenafil citrate or a placebo to prove whether the treatment is effectve. 

By increasing blood-flow to the placenta, sildenafil citrate could give growth restricted babies more time in the womb. In clinical terms, an extra week of gestation could mean huge benefits for the fetus. 

To learn more about the STRIDER, watch the video below:

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