Cow’s milk protein allergy (CMPA) is one of the first and most common food allergies reported in the paediatric population. It is also one of the main causes of anaphylaxis in the first two years if life. However, the management of CMPA is debated around the world. The majority of CMPA resolves spontaneously in childhood and hence many European countries recommend strict avoidance of all milk products. In Ireland, CMPA is treated using oral immunotherapy (OIT), also known as the milk ladder, with good results. However, novel treatments have been published recently that could lead to a different approach in the management of CMPA. One of these treatments is the use of early OIT immediately at diagnosis. This treatment option has been found to be safe and successful, and is suggestive of the possibility of a new management strategy for IgE-mediated CMPA in the future.
This study will compare three cohorts of paediatric patients diagnosed with CMPA from the three hospitals and one family health care clinic participating in this study. This retrospective analysis will compare the effectiveness of each management plan. The results of this study will help guide the future management of CMPA.