In our first seminar of the new academic year, Dr Sophie Casey will present ‘Inflammation Driven Molecular Alterations in Disorders of the Perinatal Brain’ on 24th September at 12pm.


Hypoxic ischemic encephalopathy and Autism Spectrum Disorder are time sensitive and have narrow therapeutic windows of opportunity. Despite this, diagnosis is typically performed too late to beneficially inform clinical and therapeutic decision making and is often subjective or unavailable due to injury severity or socioeconomic factors. Neonates who are diagnosed with these disorders often receive treatment too late to confer beneficial levels of protection, or treatment is inappropriate.

HIE and ASD are linked by inflammation and the involvement of inflammatory markers which may offer promising biomarker and/or therapeutic candidates.