INFANT PI, Professor Deirdre Murray announced as Chair in Early Brain Injury and Cerebral Palsy

By |2023-10-05T16:23:47+01:00October 6th, 2023|

Friday, 6 October 2023:  Today on World Cerebral Palsy Day, University College Cork (UCC) has announced the appointment of Professor Deirdre Murray as the new Chair in Early Brain Injury and Cerebral Palsy, as part of a new programme of excellence to revolutionise the delivery of cerebral palsy care in Ireland.

In May, the Cerebral Palsy Foundation (CPF) announced that UCC as one of three new clinical and research hubs to help establish Ireland as an international leader in Cerebral Palsy (CP) care and research.

As part of the programme, CPF is investing €1.6 million to advance research in early brain injury and cerebral palsy at the Irish Centre for Maternal and Child Health Research (INFANT), UCC.

A UCC alumnus, Professor Murray graduated from UCC in 1995 before completing paediatric training in Paediatric Intensive Care Medicine in Bristol Royal Hospital for Sick Children, and later working as a Paediatric Intensive care Fellow in the Royal Children’s Hospital, Melbourne. In 2012 she was awarded a prestigious Health Research Board Clinician Scientist Award for the BiHiVE study, an ongoing project focusing on the discovery and validation of biomarkers in neonatal brain injury.

A Consultant Paediatrician, Paediatric Research Lead at INFANT and Professor of Paediatrics, in UCC’s Department of Paediatrics and Child Health, Deirdre’s research is focused on early brain injury and the development of new ways to predict and assess neurocognitive outcome in children.

Rachel Byrne, Executive Director of the Cerebral Palsy Foundation, said: “We established the CP Programme of Excellence to vastly improve the care provided to people with cerebral palsy in Ireland; from childhood right through to adulthood. We know that the correct interventions at an early age can have a huge impact on the lifespan of people living with cerebral palsy. Professor Murray will lead incredibly important research on early brain injury that will inform how we treat and support children with cerebral palsy and ensure they have the best possible outcomes.”

Professor Geraldine Boylan, Director of INFANT, said: “Congratulations to Professor Deirdre Murray on her well-deserved appointment as Chair in Early Brain Injury and Cerebral Palsy at UCC.  Professor Murray’s expertise in this important leadership role will allow us to focus our early brain injury research on early detection and interventions for cerebral palsy.   We are immensely grateful to the Cerebral Palsy Foundation for this strategic funding which also highlights our growing partnership and joint commitment to effect positive change for people with cerebral palsy.”

Professor Deirdre Murray said: I am very honoured to assume the role of Chair in Early Brain Injury and Cerebral Palsy. This signifies an important step forward and I am committed to leading our research efforts at INFANT in partnership with the Cerebral Palsy Foundation, to make Ireland a leading country for research into early brain injury and more importantly to improve health outcomes for children with cerebral palsy and their families.”

Currently the most common lifelong physical disability acquired during childhood, cerebral palsy is diagnosed in approximately 150 children each year in Ireland. Early diagnosis in babies can lead to much better outcomes. The Cerebral Palsy Foundation’s partnership with UCC will enable researchers at INFANT to generate critical knowledge that will transform outcomes for children with Cerebral Palsy and their families.

Professor John F. Cryan, UCC Vice-President for Research and Innovation said: “Congratulations to Professor Deirdre Murray on her appointment as the new Chair in Early Brain Injury and Cerebral Palsy, and sincere thanks to the Cerebral Palsy Foundation for their continued partnership with UCC. In the coming months, we will launch UCC Futures – Children and UCC Futures – Ageing and Brain Science, and Professor Murray’s research expertise in early brain injury and cerebral palsy will be very important in these two areas of research prioritisation at UCC.”

Professor Helen Whelton, Head of College of Medicine and Health, UCC said: “Congratulations to Professor Deirdre Murray and INFANT Research Centre, UCC for the excellent work being done by our clinicians and researchers to help revolutionise cerebral palsy care in Ireland which will improve health outcomes and so change the trajectory of people’s lives.”

The creation of this new Chair at UCC in Early Brain Injury and Cerebral Palsy will build on an existing collaboration between the Cerebral Palsy Foundation and the INFANT Centre on the ‘Early Detection and Intervention for Cerebral Palsy in Ireland’ study. This is a national, multi-centre cohort study led by INFANT and coordinated by In4kids, the HRB Irish Network for Children’s Clinical Trials.

HRB invests €1.9 million in UCC research to address emerging health challenges

By |2023-10-04T08:12:47+01:00October 4th, 2023|

High blood pressure during pregnancy, strategies for preventing drug overdose and the factors associated with suicide risk in older adults are among the health and social care research projects to receive funding from the Health Research Board’s Postdoctoral Fellowship Scheme.

Five post-doctoral researchers at UCC’s School of Public Health, National Suicide Research Foundation (NSRF) and the Irish Centre for Maternal & child Health Research (INFANT) have received a total of €1.9 million in funding to investigate and find solutions for public health challenges.

Dr Peter Barrett, based in INFANT and the School of Public Health in UCC, has received €830,000 in research funding for his project investigating the long-term impact of hypertensive disorders of pregnancy on maternal health, and exploration of optimal models of follow-up care for affected women in Ireland.

“This project will focus on high blood pressure during pregnancy, and how we use obstetric information to predict the risk of chronic diseases in later life. We know that risk factors during pregnancy can offer insights into long-term maternal health outcomes. There are huge opportunities to harness this information for the prevention of age-related diseases in later life. I am excited to work on this project with the teams in INFANT, the School of Public Health, and with both academic and health service partners from Ireland and overseas. It is important that we apply the research findings here to affected groups in the community, and to the Irish health service,” said Dr Barrett.

The five funded post-doctoral researchers are:

  • Dr Susan CalnanImproving public health through better implementation of alcohol policy: A multimethod study examining and addressing the factors influencing successful implementation. This research will provide evidence to help policymakers and stakeholders to better understand factors that influence the successful implementation of public health alcohol policy and look at ways to improve these factors so that alcohol policies are effectively implemented to help reduce harms from alcohol. Funding amount: €255,013.
  • Dr Caroline DalyRESTRICT – REducing intentional overdose: a mixed methods STudy of means RestrICTion interventions. Submitted under the National Suicide Research Foundation – UCC Memorandum of Collaboration, this research aims to prevent intentional overdose by studying the impact of measures to restrict access to drugs. Delivered by a team of individuals from different disciplines including mental health professionals, policy makers, researchers and people with experiences of self-harm, findings from this research will provide a comprehensive understanding of intentional overdose in Ireland and inform future measures to restrict access to drugs and to prevent self-harm and suicide. Funding amount: €284,976.
  • Dr Fiona RiordanIdentifying social determinants and mapping organisational and personal networks to enhance community support for people living with multimorbidity. With people from disadvantaged communities developing chronic health conditions earlier in life, this project aims to find ways to better support people living with multiple conditions within disadvantaged areas in Ireland, and discuss the findings with a range of stakeholders, including policymakers, healthcare managers and representatives from non-clinical community services. Funding amount: €268,243.
  • Dr Isabela TroyaRevisiting suicide prevention in later life: human-centred approaches in an ageing Ireland. Annually in Ireland, over 400 people die by suicide and a further 12,000 are hospitalised following self-harm, of which 15% are older adults. The aim of this study is to improve the understanding of factors associated with self-harm and suicide risk in older adults aged >60 and thus co-produce clinical and policy guidance to reduce suicidal behaviour in older adults. Submitted under the National Suicide Research Foundation – UCC Memorandum of Collaboration, this research should help strengthen and inform national suicide prevention strategies. Funding amount: €266,416.
  • Dr Peter BarrettAn investigation of the long-term impact of hypertensive disorders of pregnancy on maternal health, and exploration of optimal models of follow-up care for affected women in Ireland. This research will answer some of the uncertainties regarding long-term risks following high blood pressure during pregnancy, using existing large-scale datasets of over 2 million mothers in Sweden and follow their progress post pregnancy for up to 48 years. Funding amount: €830,000.

Dr Mairéad O’Driscoll, HRB Chief Executive, said: “We are delighted to announce the latest round of funding in these HRB Postdoctoral Fellowship schemes. They are a key pillar in the HRB’s Research Career Framework. This framework provides a coordinated, coherent approach to building the capacity and capability of academic researchers and health and social care practitioners to respond to current and emerging health research needs.”

Congratulating the five award recipients from University College Cork on their awards, Professor John F. Cryan, UCC Vice President for Research and Innovation said: “Congratulations to these early-career researchers in receiving Health Research Board awards, in key areas which will address critical health and social care challenges. These awards will provide the researchers with an opportunity to enhance their career development and deliver on excellent societal research outcomes.”

IRC Government of Ireland Postdoctoral Fellowship and Postgraduate Scholarship Awardees

By |2023-09-15T14:13:34+01:00September 14th, 2023|

Three INFANT researchers received IRC Government of Ireland Postdoctoral Fellowship and Postgraduate Scholarship Awards.

Minister Simon Harris announced €24.6 million in Irish Research Council funding to support rising researchers and pioneering projects. “I am delighted to announce this investment for a new generation of postgraduate and postdoctoral researchers under the Irish Research Council’s Government of Ireland programmes. These awards will support the development of the next generation of excellent researchers in Ireland, as they pursue new knowledge at the cutting edge of a wide range of disciplines”.

Postdoctoral Fellowship Awardees: 

Marita Hennessy is a Postdoctoral Researcher at INFANT (Pregnancy Loss Research Group). During her two-year fellowship, Marita will develop and pilot test a psychosocial intervention for staff in maternity hospitals/units in Ireland under the mentorship of INFANT PI, Professor Keelin O’Donoghue.

Gillian Maher is a Postdoctoral Researcher at INFANT. During her two-year fellowship, Gillian will develop a novel approach to harness Irish maternal and newborn data to improve pregnancy outcomes for mothers and babies.

Postgraduate Scholarship Awardee: 

Aoife Gallagher is a Clinical Research Fellow with an interest in Pediatric Allergy and Immunology. During her 12-month scholarship she will be working on ARChhIE: A Retrospective Comparison of Irish and Spanish IgE- Medi-ated Egg Allergy Strategies.

Welcoming the announcement, Peter Brown, Director of the Irish Research Council, said: “Early-career researchers represent the future of research and innovation and the funding being announced by the Minister today will support a vibrant knowledge eco-system. This eco-system will benefit and shape the further development of enterprise, public policy and our higher education institutions”.

Born Too Soon Airs on Virgin Media One

By |2023-09-04T09:26:20+01:00September 4th, 2023|

Born Too Soon will give an unprecedented look into lives of the hardworking staff who dedicate their lives to caring for vulnerable newborns at CUH’s neonatal unit.

TV crews have been in the hospital all year filming ‘Born Too Soon,’ following the stories of families and medical teams looking after premature babies born at the busy hospital.

At CUH, preemies are given round-the-clock care, with the new series showing the ups and downs of life looking after frail babies – particularly in a time with strict Covid restrictions.

Viewers will get to see the dedication and love put into giving babies born preterm the best chance possible when Born Too Soon starts at 9 pm Tues 5 September on Virgin Media One.

INFANT Researchers Contribution to PAS 2022 Meeting

By |2022-04-20T12:04:25+01:00April 20th, 2022|

INFANT is delighted to be involved in the PAS 2022 Meeting in Denver 21-25 April.

Members of the INFANT team will join thousands of physicians, researchers, and Allied health professionals from 60 + specialty areas as they come together to share research, explore new collaboratives, and experience the best the paediatric research community has to offer.

Professor Geraldine Boylan and Professor Deirdre Murray are giving invited talks while other members of the INFANT team will be presenting oral and poster presentations.

 

See a list of INFANT speakers and schedule of presentations below:

 

Geraldine B. Boylan, PhD

Professor of Neonatal Physiology
University College Cork

Director of the Infant Research Centre, University College Cork

Presentation(s):

  • Making the Most of Neonatal Brain Monitoring

Sunday, April 24, 2022
11:35 AM – 11:50 AM US MT

  • Role of EEG and machine learning algorithms

Sunday, April 24, 2022
1:25 PM – 1:35 PM US MT

 

Deirdre M. Murray, MB BAO BcH FRCPI FPAEDPhD

Chair of the Department of Paediatrics and Child Health
University College Cork

Presentation(s):

  • Clinical importance of long term follow up

Sunday, April 24, 2022
1:15 PM – 1:25 PM US MT

 

Eugene Dempsey, FRCPI

Horgan Chair in Neonatology
University College Cork

Poster(s):

  • 463 – Early cerebral desaturation events in extremely preterm infants are associated with intraventricular haemorrhage in the first week of life

Sunday, April 24, 2022

3:30 PM – 6:00 PM US MT

 

Aisling A. Garvey, MB BCh BAO MRCPI

Neonatal Neurology Fellow
Brigham and Women’s Hospital

Boston, Massachusetts, United States

Infant Research Centre, University College Cork

Presentation(s):

  • Serial MRI facilitates early detection of White Matter Injury in Preterm infants (Poster Board 4)

Sunday, April 24, 2022
10:00 AM – 11:30 AM US MT

Poster(s):

  • 352 – Multi-modal Monitoring of Infants with Hypoxic-Ischaemic Encephalopathy and Prediction of Short-term Outcome.

Monday, April 25, 2022

3:30 PM – 6:00 PM US MT

 

Roberto Chioma, MD

Clinical Fellow
Università Cattolica del Sacro Cuore

Infant Research Centre, University College Cork

Poster(s):

  • Development of a Lung UltraSound Targeted Recruitment (LUSTR) protocol to improve the outcome in critically-ill neonates undergoing mechanical ventilation (Poster Board 3)

Saturday, April 23, 2022
10:00 AM – 11:30 AM US MT

 

David B. Healy

Research Fellow
University College Cork

Poster(s):

  • 188 – Agreement of Cardiac Output Estimates between Electrical Cardiometry and Transthoracic Echocardiography in Very Preterm Infants

Saturday, April 23, 2022

3:30 PM – 6:00 PM US MT

  • 219 – Electrical Cardiometry in the transitional Period is not associated with short-term Outcome in Very Preterm Infants

Saturday, April 23, 2022

3:30 PM – 6:00 PM US MT

  • 369 – Thoracic fluid content as measured by bioimpedance is not associated with respiratory outcome or death in very preterm infants

Monday, April 25, 2022

3:30 PM – 6:00 PM US MT

 

Mark O’Sullivan, PhD

Lead Investigator
Infant Research Centre, University College Cork

Poster(s):

544 – Neurobell: Portable EEG Monitoring with On-Board AI for Neonatal Seizure Detection

Friday, April 22, 2022

6:15 PM – 8:45 PM US MT

 

Learn more about the Pediatric Academic Societies (PAS)

and more about PAS 2022 Meeting

IWD 2022: Celebrating The Achievements of Our Female Research Team

By |2022-03-08T10:56:18+00:00March 8th, 2022|

On this International Women’s Day, we are delighted to celebrate the achievements of UCC female researchers based at the INFANT Research Centre, by demonstrating leadership in research that is transforming the future of maternal and child healthcare.

Led by Director Professor Geraldine Boylan, INFANT is answering the international need for research and innovation to improve health outcomes across the continuum of pregnancy, infancy and childhood.

Here are just examples of their work:

INFANT spin out company, Liltoda, led by Professor Deirdre Murray in collaboration with Hello Games, a global gaming company, is harnessing the power of innovative gaming technology to assess cognitive function in young children. This technology was developed by the team at INFANT and is now being rolled out across the world.

Dr. Jane English is leading a transformative study that aims to identify biomarkers in the blood (e.g. proteins or metabolites) that predict the onset of severe childhood autism. Early prediction will help support early intervention, improvements in health outcomes and enhance the quality of life of children with severe autism, and their families.

Professor Geraldine Boylan has led the world’s first clinical trial of an automated seizure detection device for newborn infants, a device which was developed by researchers at INFANT in UCC.  This technology was recently commercialised and launched in Ireland and Japan by industry partner Nihon Kohden, a Tokyo based global leader in patient monitoring technology.

Prof Mairead Kiely, Dr. Elaine McCarthy and Dr. Áine Hennessy’s are the team of female researchers leading the way internationally in maternal and child nutrition research. This team are tackling problems such as iron deficiency in pregnancy and childhood, assessing iodine status in pregnancy and have developed novel technology to support a personalised nutrition approach for preterm infants in the intensive care unit.

Dr. Mairead O’Riordan, a consultant obstetrician and gynaecologist, is leading recruitment to a clinical trial at Cork University Maternity Hospital that investigates the use of low-dose aspirin therapy for the improvement of pregnancy outcomes in women with diabetes.

Professor Keelin O’Donoghue leads pregnancy loss research at INFANT and is working closely with many stakeholders to increase awareness of pregnancy loss, to encourage more effective services/supports within the health care system and to ensure this research leads to the implementation of healthcare policy changes.

These are just some of the 53 female researchers based at INFANT who are dedicated to improving health outcomes for pregnant women, infants, and children.

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